Applied Pharmacology & Neuroscience
The mechanism
behind the headline.
I read the pharmacology papers, pull out the receptor-level mechanism, and tell you what's actually happening. No priors, no hype — just what's in the literature.
Formerly built on AAS pharmacology. Now expanding into the full breadth of applied pharmacology — psychiatric drugs, neurodegeneration, drug metabolism, and everything between.
Latest Breakdowns
Every claim, traced back to the paper it came from.
Rebuttal
SSRIs vs. What's Next
Monoamine reuptake inhibition made sense in 1987. Esketamine, zuranolone, and psilocybin argue for something else entirely.
Full script + fact-check and others
Evolutionary Psychiatry
Reser's Evolutionary Theory of Autism
Analyzing the evolutionary trade-offs and adaptive hypotheses behind neurodevelopmental variation.
Reser et al., 2011 and others
Rebuttal / SSRI Safety
SSRI Efficacy & The "Long-Term Trial" Myth
Debunking claims about the lack of long-term placebo controls and examining what trials actually demonstrate about SSRI efficacy.
Cipriani et al., 2018 and others
Neurogenesis
The Neurons You Weren't Born With
Bomb-pulse carbon-14 dating says your hippocampus is younger than you think.
Spalding et al., 2013 and others
About
An informed layperson, not a credentialed one.
I'm not a clinician, nor am I a researcher. I'm just the guy who summarizes the literature for my audience. Always trust the educated professionals for accurate scientific consensus.
- 1,000+breakdowns explained to people like you
- Weeklya new mechanism breakdown, every week
- 1goal — to publish evidence-based content for everyone to learn from
Juublian Weekly
a subscription, dispensed weekly
Sig: One breakdown, weekly. Take with morning coffee. Refills: unlimited. Side effects may include unsolicited pharmacology opinions.
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Community
The comment section is where the real debate happens.
Evolutionary theory, contested mechanisms, the papers everyone's arguing about — the community takes it further than a 70-second video can.
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The long-form version.
Everything a 70-second video can't fit — full mechanisms, full citations, full nuance — in one ebook.
1:1 Sessions
Want it tailored to your questions?
A paid session to walk through the literature on whatever you're trying to understand — how a drug class works, how to read a paper, what a claim actually rests on. Educational only, not medical advice, and not a substitute for talking to a clinician about your own care.